Retinal Laser for
RPE Cell Regeneration
R:GEN® AND CORE TECHNOLOGY
Innovative Laser Solution for Common Retinal Diseases
Selective Retina Therapy
527 nm wavelength & 1.7 µs pulse duration
Real Time Feedback Technology
RTF Sensor (Disposable)
The RTF sensor enables selective retinal treatment by detecting the pressure wave of microbubble generated after irradiation with R:GEN laser.
Ideal Wavelength and Pulse Duration (527 nm / 1.7 μs)
The R:GEN with 527 nm wavelength and 1.7 μs pulse width is ideal for selectively damaging RPE cells while sparing other retinal tissues.
Ref. JOURNAL OF THE OPTICAL SOCIETY OF AMERICA, VOL. 60, NO. 2
Bull. Soc. Belge Ophtalmol 302 (2006): 51-69.
Rapidly produce 15 laser pulses with ramping up energies to check the optimal pulses for patient.
Ref. Kim MK, et al. Graefes Arch Clin Exp Ophthalmol. 2018 Sep;256(9):1639-1651; High Resolution Imaging in Microscopy and Ophthalmology: New Frontiers in Biomedical Optics [Internet]. Cham (CH): Springer; 2019. Chapter 11.
Real-time Feedback Technology
R:GEN utilizes optoacoustic and reflectometry to ensure the appropriate treatment energy. Real-Time Feedback technology detects sound wave & back scattering light from RPE microbubbles generated by laser and irradiation automatically stops when microbubble formation is detected.
R:GEN MECHANISM OF ACTION
How R:GEN works
When problematic RPE cells are treated by R:GEN®, the irradiated RPE cells are destroyed without damaging
neighbor photoreceptors. Subsequently, RPE cell regeneration is induced which results in improvement of the retinal metabolism.
Dry Age-related Macular Degeneration (AMD)
Central Serous Chorioretinopathy (CSC)
Diabetic Macular Edema (DME)
Clinically Significant Macular Edema (CSME)